The calculated distance (air line) between Caazapá and San Isidro de Curuguaty is approximately 126 miles respectively 203 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between Caazapá and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
203 kilometers
110 nautical miles