The calculated distance (air line) between Puebla and Santa Cruz Xoxocotlán is approximately 169 miles respectively 272 kilometers.
By car or train, the actual journey to Santa Cruz Xoxocotlán is certainly longer, as only the direct route (as the crow flies) between Puebla and Santa Cruz Xoxocotlán has been calculated here.
Air line (approximately)
272 kilometers
147 nautical miles