The calculated distance (air line) between San Andrés Mixquic and Acapulco de Juárez is approximately 176 miles respectively 282 kilometers.
By car or train, the actual journey to Acapulco de Juárez is certainly longer, as only the direct route (as the crow flies) between San Andrés Mixquic and Acapulco de Juárez has been calculated here.
Air line (approximately)
282 kilometers
152 nautical miles