The calculated distance (air line) between Lomas de Sargentillo and Guayaquil is approximately 26 miles respectively 41 kilometers.
By car or train, the actual journey to Guayaquil is certainly longer, as only the direct route (as the crow flies) between Lomas de Sargentillo and Guayaquil has been calculated here.
Air line (approximately)
41 kilometers
22 nautical miles