The calculated distance (air line) between San Agustín Tlaxco and Iztapalapa is approximately 73 miles respectively 117 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between San Agustín Tlaxco and Iztapalapa has been calculated here.
Air line (approximately)
117 kilometers
63 nautical miles