The calculated distance (air line) between Nueva Esperanza and San Isidro de Curuguaty is approximately 53 miles respectively 85 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between Nueva Esperanza and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
85 kilometers
46 nautical miles