The calculated distance (air line) between Ḩamāh and Khān Shaykhūn is approximately 22 miles respectively 36 kilometers.
By car or train, the actual journey to Khān Shaykhūn is certainly longer, as only the direct route (as the crow flies) between Ḩamāh and Khān Shaykhūn has been calculated here.
Air line (approximately)
36 kilometers
19 nautical miles