The calculated distance (air line) between Portalegre and São Domingos de Rana is approximately 110 miles respectively 178 kilometers.
By car or train, the actual journey to São Domingos de Rana is certainly longer, as only the direct route (as the crow flies) between Portalegre and São Domingos de Rana has been calculated here.
Air line (approximately)
178 kilometers
96 nautical miles