The calculated distance (air line) between Loulé and São Domingos de Rana is approximately 130 miles respectively 209 kilometers.
By car or train, the actual journey to São Domingos de Rana is certainly longer, as only the direct route (as the crow flies) between Loulé and São Domingos de Rana has been calculated here.
Air line (approximately)
209 kilometers
113 nautical miles