The calculated distance (air line) between Lefkáda and Néa Smýrni is approximately 174 miles respectively 280 kilometers.
By car or train, the actual journey to Néa Smýrni is certainly longer, as only the direct route (as the crow flies) between Lefkáda and Néa Smýrni has been calculated here.
Air line (approximately)
280 kilometers
151 nautical miles