The calculated distance (air line) between Sankt Margrethen and Zürich (Kreis 4) / Aussersihl is approximately 52 miles respectively 84 kilometers.
By car or train, the actual journey to Zürich (Kreis 4) / Aussersihl is certainly longer, as only the direct route (as the crow flies) between Sankt Margrethen and Zürich (Kreis 4) / Aussersihl has been calculated here.
Air line (approximately)
84 kilometers
46 nautical miles