The calculated distance (air line) between Mendrisio and Zürich (Kreis 2) is approximately 104 miles respectively 167 kilometers.
By car or train, the actual journey to Zürich (Kreis 2) is certainly longer, as only the direct route (as the crow flies) between Mendrisio and Zürich (Kreis 2) has been calculated here.
Air line (approximately)
167 kilometers
90 nautical miles