The calculated distance (air line) between San Lorenzo and San Isidro de Curuguaty is approximately 129 miles respectively 207 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between San Lorenzo and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
207 kilometers
112 nautical miles