The calculated distance (air line) between San Juan Bautista and San Isidro de Curuguaty is approximately 177 miles respectively 285 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between San Juan Bautista and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
285 kilometers
154 nautical miles