The calculated distance (air line) between Itauguá and San Isidro de Curuguaty is approximately 122 miles respectively 196 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between Itauguá and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
196 kilometers
106 nautical miles