The calculated distance (air line) between Hohenau and San Isidro de Curuguaty is approximately 180 miles respectively 289 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between Hohenau and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
289 kilometers
156 nautical miles