The calculated distance (air line) between Guarambaré and San Isidro de Curuguaty is approximately 131 miles respectively 211 kilometers.
By car or train, the actual journey to San Isidro de Curuguaty is certainly longer, as only the direct route (as the crow flies) between Guarambaré and San Isidro de Curuguaty has been calculated here.
Air line (approximately)
211 kilometers
114 nautical miles