The calculated distance (air line) between Doctor Juan León Mallorquín and Itauguá is approximately 131 miles respectively 211 kilometers.
By car or train, the actual journey to Itauguá is certainly longer, as only the direct route (as the crow flies) between Doctor Juan León Mallorquín and Itauguá has been calculated here.
Air line (approximately)
211 kilometers
114 nautical miles