The calculated distance (air line) between Enriquillo and San Francisco de Macorís is approximately 116 miles respectively 187 kilometers.
By car or train, the actual journey to San Francisco de Macorís is certainly longer, as only the direct route (as the crow flies) between Enriquillo and San Francisco de Macorís has been calculated here.
Air line (approximately)
187 kilometers
101 nautical miles