The calculated distance (air line) between Álvaro Obregón and Guanajuato is approximately 176 miles respectively 283 kilometers.
By car or train, the actual journey to Guanajuato is certainly longer, as only the direct route (as the crow flies) between Álvaro Obregón and Guanajuato has been calculated here.
Air line (approximately)
283 kilometers
153 nautical miles