The calculated distance (air line) between Tlacotepec and Iztapalapa is approximately 103 miles respectively 166 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between Tlacotepec and Iztapalapa has been calculated here.
Air line (approximately)
166 kilometers
89 nautical miles