The calculated distance (air line) between Tlacotepec and Iztapalapa is approximately 124 miles respectively 199 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between Tlacotepec and Iztapalapa has been calculated here.
Air line (approximately)
199 kilometers
107 nautical miles