The calculated distance (air line) between Santiago Juxtlahuaca and Iztapalapa is approximately 156 miles respectively 251 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between Santiago Juxtlahuaca and Iztapalapa has been calculated here.
Air line (approximately)
251 kilometers
135 nautical miles