The calculated distance (air line) between Santa María Xonacatepec and Iztapalapa is approximately 65 miles respectively 105 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between Santa María Xonacatepec and Iztapalapa has been calculated here.
Air line (approximately)
105 kilometers
57 nautical miles