The calculated distance (air line) between Ixhuatlán del Café and Iztapalapa is approximately 137 miles respectively 221 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between Ixhuatlán del Café and Iztapalapa has been calculated here.
Air line (approximately)
221 kilometers
119 nautical miles