The calculated distance (air line) between Yaguajay and Sancti Spíritus is approximately 30 miles respectively 49 kilometers.
By car or train, the actual journey to Sancti Spíritus is certainly longer, as only the direct route (as the crow flies) between Yaguajay and Sancti Spíritus has been calculated here.
Air line (approximately)
49 kilometers
26 nautical miles