The calculated distance (air line) between Cienfuegos and San Miguel del Padrón is approximately 137 miles respectively 220 kilometers.
By car or train, the actual journey to San Miguel del Padrón is certainly longer, as only the direct route (as the crow flies) between Cienfuegos and San Miguel del Padrón has been calculated here.
Air line (approximately)
220 kilometers
119 nautical miles