The calculated distance (air line) between Cienfuegos and Güira de Melena is approximately 139 miles respectively 224 kilometers.
By car or train, the actual journey to Güira de Melena is certainly longer, as only the direct route (as the crow flies) between Cienfuegos and Güira de Melena has been calculated here.
Air line (approximately)
224 kilometers
121 nautical miles