The calculated distance (air line) between Santa Catarina Ixtahuacán and Mixco is approximately 52 miles respectively 83 kilometers.
By car or train, the actual journey to Mixco is certainly longer, as only the direct route (as the crow flies) between Santa Catarina Ixtahuacán and Mixco has been calculated here.
Air line (approximately)
83 kilometers
45 nautical miles