The calculated distance (air line) between San Andrés Itzapa and Chiquimula is approximately 88 miles respectively 141 kilometers.
By car or train, the actual journey to Chiquimula is certainly longer, as only the direct route (as the crow flies) between San Andrés Itzapa and Chiquimula has been calculated here.
Air line (approximately)
141 kilometers
76 nautical miles