The calculated distance (air line) between Panajachel and Santa Cruz del Quiché is approximately 20 miles respectively 32 kilometers.
By car or train, the actual journey to Santa Cruz del Quiché is certainly longer, as only the direct route (as the crow flies) between Panajachel and Santa Cruz del Quiché has been calculated here.
Air line (approximately)
32 kilometers
17 nautical miles