The calculated distance (air line) between Ciudad Guayana and San José de Guanipa is approximately 111 miles respectively 178 kilometers.
By car or train, the actual journey to San José de Guanipa is certainly longer, as only the direct route (as the crow flies) between Ciudad Guayana and San José de Guanipa has been calculated here.
Air line (approximately)
178 kilometers
96 nautical miles