The calculated distance (air line) between Santa Clara and Ciudad Camilo Cienfuegos is approximately 159 miles respectively 256 kilometers.
By car or train, the actual journey to Ciudad Camilo Cienfuegos is certainly longer, as only the direct route (as the crow flies) between Santa Clara and Ciudad Camilo Cienfuegos has been calculated here.
Air line (approximately)
256 kilometers
138 nautical miles