The calculated distance (air line) between Medellín y Madero Segunda Sección and Tuxtla is approximately 95 miles respectively 153 kilometers.
By car or train, the actual journey to Tuxtla is certainly longer, as only the direct route (as the crow flies) between Medellín y Madero Segunda Sección and Tuxtla has been calculated here.
Air line (approximately)
153 kilometers
83 nautical miles