The calculated distance (air line) between San Marcos Yachihuacaltepec and Iztapalapa is approximately 40 miles respectively 65 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between San Marcos Yachihuacaltepec and Iztapalapa has been calculated here.
Air line (approximately)
65 kilometers
35 nautical miles