The calculated distance (air line) between San Mateo Otzacatipan and Iztapalapa is approximately 35 miles respectively 57 kilometers.
By car or train, the actual journey to Iztapalapa is certainly longer, as only the direct route (as the crow flies) between San Mateo Otzacatipan and Iztapalapa has been calculated here.
Air line (approximately)
57 kilometers
31 nautical miles