The calculated distance (air line) between Santa María del Río and Ecatepec de Morelos is approximately 186 miles respectively 300 kilometers.
By car or train, the actual journey to Ecatepec de Morelos is certainly longer, as only the direct route (as the crow flies) between Santa María del Río and Ecatepec de Morelos has been calculated here.
Air line (approximately)
300 kilometers
162 nautical miles