The calculated distance (air line) between San Luis Potosí and Zacatecas is approximately 111 miles respectively 178 kilometers.
By car or train, the actual journey to Zacatecas is certainly longer, as only the direct route (as the crow flies) between San Luis Potosí and Zacatecas has been calculated here.
Air line (approximately)
178 kilometers
96 nautical miles