The calculated distance (air line) between Tlaltenango de Sánchez Román and Guadalajara is approximately 77 miles respectively 124 kilometers.
By car or train, the actual journey to Guadalajara is certainly longer, as only the direct route (as the crow flies) between Tlaltenango de Sánchez Román and Guadalajara has been calculated here.
Air line (approximately)
124 kilometers
67 nautical miles