The calculated distance (air line) between Ishtixon Shahri and Tŭytepa is approximately 168 miles respectively 271 kilometers.
By car or train, the actual journey to Tŭytepa is certainly longer, as only the direct route (as the crow flies) between Ishtixon Shahri and Tŭytepa has been calculated here.
Air line (approximately)
271 kilometers
146 nautical miles