The calculated distance (air line) between Shaykh Miskīn and Khān Shaykhūn is approximately 183 miles respectively 294 kilometers.
By car or train, the actual journey to Khān Shaykhūn is certainly longer, as only the direct route (as the crow flies) between Shaykh Miskīn and Khān Shaykhūn has been calculated here.
Air line (approximately)
294 kilometers
159 nautical miles