The calculated distance (air line) between Nubl and Khān Shaykhūn is approximately 67 miles respectively 109 kilometers.
By car or train, the actual journey to Khān Shaykhūn is certainly longer, as only the direct route (as the crow flies) between Nubl and Khān Shaykhūn has been calculated here.
Air line (approximately)
109 kilometers
59 nautical miles