The calculated distance (air line) between Ma‘arratmişrīn and As Safīrah is approximately 39 miles respectively 63 kilometers.
By car or train, the actual journey to As Safīrah is certainly longer, as only the direct route (as the crow flies) between Ma‘arratmişrīn and As Safīrah has been calculated here.
Air line (approximately)
63 kilometers
34 nautical miles