The calculated distance (air line) between Izra‘ and Khān Shaykhūn is approximately 179 miles respectively 289 kilometers.
By car or train, the actual journey to Khān Shaykhūn is certainly longer, as only the direct route (as the crow flies) between Izra‘ and Khān Shaykhūn has been calculated here.
Air line (approximately)
289 kilometers
156 nautical miles