The calculated distance (air line) between I‘zāz and Khān Shaykhūn is approximately 82 miles respectively 132 kilometers.
By car or train, the actual journey to Khān Shaykhūn is certainly longer, as only the direct route (as the crow flies) between I‘zāz and Khān Shaykhūn has been calculated here.
Air line (approximately)
132 kilometers
71 nautical miles