The calculated distance (air line) between Veselí nad Lužnicí and Karlovy Vary is approximately 109 miles respectively 176 kilometers.
By car or train, the actual journey to Karlovy Vary is certainly longer, as only the direct route (as the crow flies) between Veselí nad Lužnicí and Karlovy Vary has been calculated here.
Air line (approximately)
176 kilometers
95 nautical miles