The calculated distance (air line) between Ledeč nad Sázavou and Karlovy Vary is approximately 113 miles respectively 182 kilometers.
By car or train, the actual journey to Karlovy Vary is certainly longer, as only the direct route (as the crow flies) between Ledeč nad Sázavou and Karlovy Vary has been calculated here.
Air line (approximately)
182 kilometers
98 nautical miles