The calculated distance (air line) between Eusebio Ayala and Caazapá is approximately 67 miles respectively 108 kilometers.
By car or train, the actual journey to Caazapá is certainly longer, as only the direct route (as the crow flies) between Eusebio Ayala and Caazapá has been calculated here.
Air line (approximately)
108 kilometers
58 nautical miles