The calculated distance (air line) between Mariano Roque Alonso and Nueva Esperanza is approximately 175 miles respectively 281 kilometers.
By car or train, the actual journey to Nueva Esperanza is certainly longer, as only the direct route (as the crow flies) between Mariano Roque Alonso and Nueva Esperanza has been calculated here.
Air line (approximately)
281 kilometers
152 nautical miles