The calculated distance (air line) between Mariano Roque Alonso and Caazapá is approximately 100 miles respectively 160 kilometers.
By car or train, the actual journey to Caazapá is certainly longer, as only the direct route (as the crow flies) between Mariano Roque Alonso and Caazapá has been calculated here.
Air line (approximately)
160 kilometers
86 nautical miles